BDBM22985 Aralen::CHEMBL76::CHLOROQUINE PHOSPHATE::Chlorochin::Chloroquine::Chloroquine, 17::med.21724, Compound 8::{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine

SMILES CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI Key InChIKey=WHTVZRBIWZFKQO-UHFFFAOYSA-N

Data  12 KI  52 IC50  1 Kd  12 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22985   

TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataEC50:  4.70E+4nMAssay Description:Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Goethe University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataEC50:  5.00E+4nMAssay Description:Agonist activity at Nurr1 ligand binding domain (unknown origin) measured by Gal4-based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed